Article
Differences in BRAF V600E mutation between the epithelium and mesenchyme in classic ameloblastoma.
Oral surgery, oral medicine, oral pathology and oral radiology - 1 Dec 2024
Chen Zhuoxuan, Hong Yingying, Zhao Zhenni, Wu Ningxiang, Ma Xiaokun, Chen Linlin, Zhang Ran
Abstract excerpt
OBJECTIVE: Laser capture microdissection (LCM) was used to pinpoint the mutated tissue in ameloblastoma and investigate whether B-Raf proto-oncogene, serine/threonine kinase (BRAF) mutation is the main pathogenic gene in classic ameloblastoma. STUDY DESIGN: A total of 24 patients with ameloblastoma scheduled to undergo surgery between 2000 and 2024 were included in the study. LCM was used to isolate tumor cells....
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