Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular defects in BRAF wild-type ameloblastomas and craniopharyngiomas-differences in mutation profiles in epithelial-derived oropharyngeal neoplasms.

Virchows Archiv : an international journal of pathology - 1 Jun 2018

Bartels Stephan, Adisa Akinyele, Aladelusi Timothy, Lemound Juliana, Stucki-Koch Angelika, Hussein Sami, Kreipe Hans, Hartmann Christian, Lehmann Ulrich, Hussein Kais

Abstract excerpt

The aim of this study was to evaluate the mutation profile of BRAF wild-type craniopharyngiomas and ameloblastomas. Pre-screening by immunohistochemistry and pyrosequencing for identifying BRAF wild-type tumors was performed on archived specimens of ameloblastic tumors (n = 20) and craniopharyngiomas (n = 62). Subsequently, 19 BRAF wild-type tumors (nine ameloblastic tumors and ten craniopharyngiomas) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ameloblastoma
Share to Craniopharyngioma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Neoplasms, Glandular and Epithelial

Share to Oropharyngeal Neoplasms

Share to Pituitary Neoplasms

Share to Proto-Oncogene Proteins B-raf

Share to Receptor, Fibroblast Growth Factor, Type 1

Source

Identifiers

PMID: 29546640
DOI: 10.1007/s00428-018-2323-3

Genes

BRAF
CTNNB1
FGFR2
FGFR3
KRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular defects in BRAF wild-type ameloblastomas and craniopharyngiomas-differences in mutation profiles in epithelial-derived oropharyngeal neoplasms.PMID 29546640Read ↗

Activating FGFR2-RAS-BRAF mutations in ameloblastoma.Semantic proximity Read ↗

Integrating genotype-phenotype correlations into the diagnostic workflow of odontogenic tumors and cysts: insights from a 69 lesion cohort.Semantic proximity Read ↗

Genomic drivers in craniopharyngiomas: Analysis of the AACR project GENIE database.Semantic proximity Read ↗

The landscape of genetic alterations in ameloblastomas relates to clinical features.Semantic proximity Read ↗

Mutational Landscape of Ameloblastoma: Analysis of BRAF and Other Key Mutations in Chinese PatientsSemantic proximity Read ↗

Characterization of novel CTNNB1 mutation in Craniopharyngioma by whole-genome sequencing.Semantic proximity Read ↗

Next-generation sequencing of oncogenes and tumor suppressor genes in odontogenic myxomas.Semantic proximity Read ↗

The Molecular Pathology of Odontogenic Tumors: Expanding the Spectrum of MAPK Pathway Driven TumorsSemantic proximity Read ↗

Prevalence and clinicopathological correlation of BRAF V600E mutations in ameloblastoma: A PCR study from a tertiary centre in South India.Semantic proximity Read ↗

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.Semantic proximity Read ↗

Ameloblastoma: A succinct review of the classification, genetic understanding and novel molecular targeted therapies.Semantic proximity Read ↗

Molecular diagnostics in odontogenic tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.