Article
Genomic profiling and precision medicine in complex ameloblastoma.
Head & neck - 1 Apr 2023
Gates James C, Clark Allison P, Cherkas Elliot, Shreenivas Aditya V, Kraus Dennis, Danzinger Natalie, Huang Richard S P, Johnson Jennifer, Ross Jeffrey S
Abstract excerpt
BACKGROUND: Ameloblastoma may present a significant treatment challenge in the locally advanced, recurrent and metastatic setting. Comprehensive genomic profiling (CGP) can identify targetable genomic alterations to aid in treatment. METHODS: Ameloblastoma samples were sequenced using hybrid-capture based sequencing. A systematic literature review was performed to examine outcomes in studies employing targeted...
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