Article
The links among age, sex, and glutathione: A cross-sectional magnetic resonance spectroscopy study.
Neurobiology of aging - 1 Dec 2024
Michels Lars, O'Gorman-Tuura Ruth, Bachmann Dario, Müller Susanne, Studer Sandro, Saake Antje, Gruber Esmeralda, Rauen Katrin, Buchmann Andreas, Zuber Isabelle, Hock Christoph, Gietl Anton, Treyer Valerie
Abstract excerpt
Glutathione (GSH) is a brain marker for oxidative stress and has previously been associated with cerebral amyloid deposition and memory decline. However, to date, no study has examined the links among GSH, sex, age, amyloid, and Apolipoprotein E (APOE) genotype in a large non-clinical cohort of older adults. We performed APOE genotyping, magnetic resonance spectroscopy (MRS) as well as simultaneous positron...
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