Article
Characterizations of Gene Alterations in Melanoma Patients from Chinese Population.
BioMed research international - 1 Jan 2020
Luo Yi, Zhang Zhenzhen, Liu Jianfan, Li Linqing, Xu Xuezheng, Yao Xinyu, Dai Zixun, Wang Xin, Yang Shuo, Wu Hongwei, Bu Jie, Wu Yuan, Xiang Tianmin, Li Xianan
Abstract excerpt
Melanoma is a human skin malignant tumor with high invasion and poor prognosis. The limited understanding of genomic alterations in melanomas in China impedes the diagnosis and therapeutic strategy selection. We conducted comprehensive genomic profiling of melanomas from 39 primary and metastatic formalin-fixed paraffin-embedded (FFPE) samples from 27 patients in China based on an NGS panel of 223 genes. No...
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