A common variant in PIK3CG gene associated with the prognosis of heart failure.

doi:10.1111/jcmm.70069

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Article

A common variant in PIK3CG gene associated with the prognosis of heart failure.

Journal of cellular and molecular medicine - 1 Sept 2024

Hu Dong, Xiao Lei, Li Shiyang

Abstract excerpt

Phosphoinositide 3-kinase γ (PI3Kγ) is G-protein-coupled receptor-activated lipid kinase with both kinase-dependent and kinase-independent activity. Plenty of evidence have demonstrated that PI3Kγ participated in TAC and I/R-induced myocardial remodelling and heart failure (HF). In this study, we tested the hypothesis that common variants in the PI3Kγ gene (PIK3CG) were associated with the prognosis of HF in the...

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Identifiers

PMID: 39245801
DOI: 10.1111/jcmm.70069
PMCID: PMC11381188

Genes

PIK3CG

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