Article
Microglial morphological/inflammatory phenotypes and endocannabinoid signaling in a preclinical model of periodontitis and depression.
Journal of neuroinflammation - 8 Sept 2024
Robledo-Montaña Javier, Díaz-García César, Martínez María, Ambrosio Nagore, Montero Eduardo, Marín María José, Virto Leire, Muñoz-López Marina, Herrera David, Sanz Mariano, Leza Juan Carlos, García-Bueno Borja, Figuero Elena, Martín-Hernández David
Abstract excerpt
BACKGROUND: Depression is a chronic psychiatric disease of multifactorial etiology, and its pathophysiology is not fully understood. Stress and other chronic inflammatory pathologies are shared risk factors for psychiatric diseases, and comorbidities are features of major depression. Epidemiological evidence suggests that periodontitis, as a source of low-grade chronic systemic inflammation, may be associated...
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