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The role of cyclic nucleotides in bacterial antimicrobial resistance and tolerance

6 Sept 2024

Abstract excerpt

Nucleotide signalling molecules - mainly cyclic 3',5'-adenosine phosphate (cAMP), bis-(3',5')-cyclic diguanosine monophosphate (c-di-GMP), and bis-(3',5')-cyclic diadenosine monophosphate (c-di-AMP) - contribute to the regulation of cellular pathways. Numerous recent works have focused on the involvement of these cyclic nucleotide phosphates (cNPs) in bacterial resistance and tolerance to antimicrobial treatment....

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PMID: 39242230
DOI: 10.1016/j.tim.2024.08.006

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