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Article

Implementing a pharmacogenomic-driven algorithm to guide antiplatelet therapy among Caribbean Hispanics: a non-randomised clinical trial.

BMJ open - 5 Sept 2024

Nuñez-Medina Hector J, Monero Mariangeli, Torres Lorna M, Leal Enrique, Gonzalez-Sepulveda Lorena, Mayor Ángel M, Renta Jessicca Y, González-García Edgardo R, González Ariel, Melin Kyle, Scott Stuart A, Ruaño Gualberto, Hernandez-Suarez Dagmar F, Duconge Jorge

Abstract excerpt

OBJECTIVES: To assess whether genotype-guided selection of oral antiplatelet drugs using a clinical decision support (CDS) algorithm reduces the rate of major adverse cardiovascular and cerebrovascular events (MACCEs) among Caribbean Hispanic patients, after 6 months. DESIGN: An open-label, multicentre, non-randomised clinical trial. SETTING: Eight secondary and tertiary care hospitals (public and private) in...

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Identifiers

PMID: 39242160
DOI: 10.1136/bmjopen-2024-084119
PMCID: PMC11381646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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