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Furanone quorum-sensing inhibitors with potential as novel therapeutics against Pseudomonas aeruginosa

23 Jan 2020

Abstract excerpt

Micro-organisms use quorum sensing (QS), a cell density-dependent process, to communicate. This QS mode of interchange leads to the production of a variety of virulence factors, co-ordination of complex bacterial behaviours, such as swarming motility, degradation of host tissue and biofilm formation. QS is implicated in numerous human infections and consequently researchers have sought ways of effectively...

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PMID: 31971503
DOI: 10.1099/jmm.0.001144

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