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Quorum sensing inhibitors: a patent review (2014–2018)

27 Oct 2018

Abstract excerpt

Introduction: Quorum sensing (QS) is a cell density-dependent phenomenon in which specific pathways are activated after autoinducers (AIs) outside the microorganism reach a threshold concentration. QS creates a positive feedback loop that induces a cascade of gene expression and causes biofilm formation, virulence and sporulation. QS signals are diverse, acyl-homoserine lactone (AHL), AI peptide (AIP) and AI-2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30366511
DOI: 10.1080/13543776.2018.1541174

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