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Extended kinship analysis of historical remains using SNP capture.

Forensic science international. Genetics - 1 Mar 2022

Gorden Erin M, Greytak Ellen M, Sturk-Andreaggi Kimberly, Cady Janet, McMahon Timothy P, Armentrout Steven, Marshall Charla

Abstract excerpt

DNA-assisted identification of historical remains requires the genetic analysis of highly degraded DNA, along with a comparison to DNA from known relatives. This can be achieved by targeting single nucleotide polymorphisms (SNPs) using a hybridization capture and next-generation sequencing approach suitable for degraded skeletal samples. In the present study, two SNP capture panels were designed to target ~...

Topics

DNA Fingerprinting
Forensic Genetics
High-Throughput Nucleotide Sequencing
Humans
Likelihood Functions
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34896972
DOI: 10.1016/j.fsigen.2021.102636

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