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Preservation of cfRNA in cytological supernatants for cfDNA & cfRNA double detection in non-small cell lung cancer patients.

Cancer medicine - 1 Sept 2024

Ma Yidan, Wang Yifei, He Lei, Du Jun, Li Lin, Bie Zhixin, Li Yuanming, Xu Xiaomao, Zhou Wei, Wu Xiaonan, Yang Li, Di Jing, Li Chenyang, Li Xiaoguang, Liu Dongge, Wang Zheng

Abstract excerpt

BACKGROUD: Supernatants from various cytological samples, including body cavity effusion, sputum, bronchoalveolar lavage fluid (BALF), and needle aspiration, have been validated for detecting genetic alterations using cell-free DNA (cfDNA) in patients with non-small cell lung cancer (NSCLC). However, the sensitivity of fusion variations detection remains challenging. The protection of cell-free RNA (cfRNA) is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39233657
DOI: 10.1002/cam4.70197
PMCID: PMC11375324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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