Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preservation of cell-free RNA in percutaneous core-needle biopsy specimens' supernatants from non-small cell lung cancer improves genomic testing performance.

The journal of pathology. Clinical research - 1 Mar 2026

Xu Sheng, Ma Yi-Dan, Bie Zhi-Xin, Huang Jing-Yu, Li Yuan-Ming, Wang Zheng, Li Xiao-Guang

Abstract excerpt

This prospective single-center study aimed to investigate whether preserving cell-free ribonucleic acid (cfRNA) in specimens' supernatants (SS) obtained from percutaneous core-needle biopsy (CNB) of non-small cell lung cancer (NSCLC) can improve the performance of genomic testing. Forty-three NSCLC patients who underwent image-guided CNB were enrolled. The SS from each CNB specimen was divided into two parts: one...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

Share to Cell-Free Nucleic Acids

Share to ROS1 gene

Share to Genetic Testing

Share to Lung Neoplasms

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 41748474
DOI: 10.1002/2056-4538.70081
PMCID: PMC12945666

Genes

ALK
MET
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preservation of cell-free RNA in percutaneous core-needle biopsy specimens' supernatants from non-small cell lung cancer improves genomic testing performance.PMID 41748474Read ↗

Preservation of cfRNA in cytological supernatants for cfDNA & cfRNA double detection in non-small cell lung cancer patients.Semantic proximity Read ↗

Circulating cell-free nucleic acids and platelets as a liquid biopsy in the provision of personalized therapy for lung cancer patients.Semantic proximity Read ↗

[Effect of storage time for non-small cell lung cancer FFPE samples on DNA detection using capture-based next-generation sequencing].Semantic proximity Read ↗

Detection and comparison of EGFR mutations from supernatants that contain cell-free DNA and cell pellets from FNA non-small cell lung cancer specimens.Semantic proximity Read ↗

Performance characteristics of a polymerase chain reaction-based assay for the detection of EGFR mutations in plasma cell-free DNA from patients with non-small cell lung cancer using cell-free DNA collection tubes.Semantic proximity Read ↗

Performance of a 50-gene next generation sequencing panel with post-centrifuge supernatant cytology fluid in non-small-cell lung cancer.Semantic proximity Read ↗

Isolation and Retrieval of Extracellular Vesicles for Liquid Biopsy of Malignant Ground-Glass OpacitySemantic proximity Read ↗

Comparison of cytocentrifugation supernatant fluid and formalin‐fixed paraffin‐embedded tissue for targeted next‐generation sequencingSemantic proximity Read ↗

The utility of sputum supernatant as an alternative liquid biopsy specimen for next-generation sequencing-based genomic profilingSemantic proximity Read ↗

Supernatant fluid from endobronchial ultrasound-guided transbronchial needle aspiration for rapid next-generation sequencing.Semantic proximity Read ↗

Next‐generation sequencing of liquid‐based cytology non–small cell lung cancer samplesSemantic proximity Read ↗

Improvement Strategies for Successful Next-Generation Sequencing Analysis of Lung CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.