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Uncovering novel regulatory variants in carbohydrate metabolism: a comprehensive multi-omics study of glycemic traits in the Indian population.

Molecular genetics and genomics : MGG - 4 Sept 2024

Nair Janaki M, Bandesh Khushdeep, Giri Anil K, Prasad Gauri, Rajashekhar Donaka, Jha Punam, Basu Analabha, Tandon Nikhil, Bharadwaj Dwaipayan

Abstract excerpt

Clinical biomarkers such as fasting glucose, HbA1c, and fasting insulin, which gauge glycemic status in the body, are highly influenced by diet. Indians are genetically predisposed to type 2 diabetes and their carbohydrate-centric diet further elevates the disease risk. Despite the combined influence of genetic and environmental risk factors, Indians have been inadequately explored in the studies of glycemic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39230791
DOI: 10.1007/s00438-024-02176-9

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