Article
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
Nature genetics - 11 Sept 2011
Kim Young Jin, Go Min Jin, Hu Cheng, Hong Chang Bum, Kim Yun Kyoung, Lee Ji Young, Hwang Joo-Yeon, Oh Ji Hee, Kim Dong-Joon, Kim Nam Hee, Kim Soeui, Hong Eun Jung, Kim Ji-Hyun, Min Haesook, Kim Yeonjung, Zhang Rong, Jia Weiping, Okada Yukinori, Takahashi Atsushi, Kubo Michiaki, Tanaka Toshihiro, Kamatani Naoyuki, Matsuda Koichi, Park Taesung, Oh Bermseok, Kimm Kuchan, Kang Daehee, Shin Chol, Cho Nam H, Kim Hyung-Lae, Han Bok-Ghee, Lee Jong-Young, Cho Yoon Shin
Abstract excerpt
To identify the genetic bases for nine metabolic traits, we conducted a meta-analysis combining Korean genome-wide association results from the KARE project (n = 8,842) and the HEXA shared control study (n = 3,703). We verified the associations of the loci selected from the discovery meta-analysis in the replication stage (30,395 individuals from the BioBank Japan genome-wide association study and individuals...
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