Article
The association between testosterone, estradiol, estrogen sulfotransferase and idiopathic pulmonary fibrosis: a bidirectional mendelian randomization study.
BMC pulmonary medicine - 3 Sept 2024
Xu Qingying, Hu Guangwang, Lin Qunying, Wu Menghang, Tang Kenan, Zhang Yuyu, Chen Feng
Abstract excerpt
BACKGROUND: The causal relationships between testosterone, estradiol, estrogen sulfotransferase, and idiopathic pulmonary fibrosis (IPF) are not well understood. This study employs a bidirectional two-sample Mendelian Randomization (MR) approach to explore these associations. METHODS: All genetic data utilized in our study were obtained from the IEU Open GWAS project. For the MR analysis, we employed the inverse...
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