Article
Mendelian randomization study reveals causal associations between plasma metabolites, immune cell phenotypes, and ovarian hyperstimulation syndrome.
Journal of reproductive immunology - 1 Jun 2025
Chen Shanshan, Yao Bo, Wang Yanting, Wang Jing, Gu Ying, Chen Xuanyi
Abstract excerpt
In this study, we employed Mendelian randomization (MR) analysis to explore the causal relationships between immune cell phenotypes, plasma metabolites, and ovarian hyperstimulation syndrome (OHSS). Through the analysis of 731 immune cell phenotypes and 1400 plasma metabolites, we identified 32 immune cell phenotypes that are causally related to OHSS, with 18 phenotypes identified as protective and 14 as risk...
Read the complete abstract on PubMedTopics
- Humans
- Female
- Mendelian Randomization Analysis
- Ovarian Hyperstimulation Syndrome
- Phenotype
- Risk Factors
