Article

Identification of immune-related hub genes and potential molecular mechanisms involved in COVID-19 via integrated bioinformatics analysis

2024-09-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>COVID-19, caused by the SARS-CoV-2 virus, poses significant health challenges worldwide, particularly due to severe immune-related complications. Understanding the molecular mechanisms and identifying key immune-related genes (IRGs) involved in COVID-19 pathogenesis are critical for developing effective therapeutic strategies. <bold>Methods:</bold> This study int...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3dea22e3-36cd-57e6-a385-010720c7d4d2
DOI: 10.21203/rs.3.rs-4706871/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of immune-related hub genes and potential molecular mechanisms involved in COVID-19 via integrated bioinformatics analysisDOI 10.21203/rs.3.rs-4706871/v1Read

Identification of potentional immunological biomarkers of COVID-19 by blood transcriptome analysisSemantic proximity Read

Identification of key genes related to immune cells in patients with COVID-19 via Integrated Bioinformatics-Based AnalysisSemantic proximity Read

Targeting hub genes and pathways of innate immune response in COVID-19: A network biology perspectiveSemantic proximity Read

COVID-19 Mortality is Associated with Impaired Innate Immunity in Pre-existing Health ConditionsSemantic proximity Read

Systems-level profiling of early peripheral host-response landscape variations across COVID-19 severity states in an Indian cohort.Semantic proximity Read

Analysis and identification of potential type II helper T cell (Th2)-Related key genes and therapeutic agents for COVID-19Semantic proximity Read

Integrated Transcriptomic Analysis Reveals Distinct Immune Response Signatures and Prognostic Biomarkers in SARS-CoV-2 InfectionSemantic proximity Read

Depicting the innate immune response landscape in Covid-19 emphasized type 1 interferon a key defense against SARS-CoV-2Semantic proximity Read

Computational Profiling of Inflammatory and Coagulation Responses in COVID-19 via RNA-SeqSemantic proximity Read

Integrative Transcriptomic Profiling of NK Cells and Monocytes: Advancing Diagnostic and Therapeutic Strategies for COVID-19Semantic proximity Read

Identification and evaluation of candidate COVID-19 critical genes and medicinal drugs related to plasma cellsSemantic proximity Read

Transcriptome‐wide summary data‐based Mendelian randomization analysis reveals 38 novel genes associated with severe COVID‐19Semantic proximity Read