Article

Multi-ancestry omic Mendelian randomization revealing putative drug targets of COVID-19 severity

2020-05-11

Abstract excerpt

Recent omic studies prioritised several drug targets associated with coronavirus disease 2019 (COVID-19) severity. However, little evidence was provided to systematically estimate the effect of drug targets on COVID-19 severity in multiple ancestries. In this study, we applied Mendelian randomization (MR) and colocalization approaches to understand the putative causal effects of 16,059 transcripts and 1,608 protei...

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Literature Corpus work: e842eadb-dba4-54a1-a112-3af8daaf5b7e
DOI: 10.1101/2020.05.07.20093286

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