Article
Genome-wide Mendelian randomization and single-cell RNA sequencing analyses identify the causal effects of COVID-19 on 41 cytokines.
Briefings in functional genomics - 17 Nov 2022
Wang Chao, Yu Rui, Zhang Sainan, Zhao Yue, Qi Changlu, Zhu Zijun, Chen Xinyu, Bi Jianxing, Xu Peigang, Cheng Liang, Zhang Xue
Abstract excerpt
The elevated levels of inflammatory cytokines have attracted much attention during the treatment of COVID-19 patients. The conclusions of current observational studies are often controversial in terms of the causal effects of COVID-19 on various cytokines because of the confounding factors involving underlying diseases. To resolve this problem, we conducted a Mendelian randomization analysis by integrating the...
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