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Article

ATM controls meiotic DNA double-strand break formation and recombination and affects synaptonemal complex organization in plants.

The Plant cell - 2 Jul 2021

Kurzbauer Marie-Therese, Janisiw Michael Peter, Paulin Luis F, Prusén Mota Ignacio, Tomanov Konstantin, Krsicka Ondrej, Haeseler Arndt von, Schubert Veit, Schlögelhofer Peter

Abstract excerpt

Meiosis is a specialized cell division that gives rise to genetically distinct gametic cells. Meiosis relies on the tightly controlled formation of DNA double-strand breaks (DSBs) and their repair via homologous recombination for correct chromosome segregation. Like all forms of DNA damage, meiotic DSBs are potentially harmful and their formation activates an elaborate response to inhibit excessive DNA break...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33659989
DOI: 10.1093/plcell/koab045
PMCID: PMC8254504

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