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The Arabidopsis thaliana DSB formation (AtDFO) gene is required for meiotic double-strand break formation.

The Plant journal : for cell and molecular biology - 1 Oct 2012

Zhang Cheng, Song Yao, Cheng Zhi-hao, Wang Ying-xiang, Zhu Jun, Ma Hong, Xu Ling, Yang Zhong-Nan

Abstract excerpt

DNA double-strand break (DSB) formation is the initial event for meiotic recombination catalyzed by the conserved Spo11 protein. In Arabidopsis, several proteins have been reported to be involved in DSB formation. Here, we report an Arabidopsis DSB forming (DFO) gene in Arabidopsis that is involved in DSB formation. The dfo mutant exhibits reduced fertility, producing polyads with an abnormal number of...

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Source

Identifiers

PMID: 22694475
DOI: 10.1111/j.1365-313X.2012.05075.x

Genes

SPO11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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