Article
Small nucleolar RNA host gene 18 controls vascular smooth muscle cell contractile phenotype and neointimal hyperplasia.
Cardiovascular research - 29 May 2024
Niu Kaiyuan, Zhang Chengxin, Yang Mei, Maguire Eithne Margaret, Shi Zhenning, Sun Shasha, Wu Jianping, Liu Chenxin, An Weiwei, Wang Xinxin, Gao Shan, Ge Shenglin, Xiao Qingzhong
Abstract excerpt
AIMS: Long non-coding RNA (LncRNA) small nucleolar RNA host gene 18 (SNHG18) has been widely implicated in cancers. However, little is known about its functional involvement in vascular diseases. Herein, we attempted to explore a role for SNHG18 in modulating vascular smooth muscle cell (VSMC) contractile phenotype and injury-induced neointima formation. METHODS AND RESULTS: Analysis of single-cell RNA sequencing...
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