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Article

Human breast tumor derived endothelial cells exhibit distinct biological properties

10 Nov 2021

Abstract excerpt

BACKGROUND INFORMATION: Excessive angiogenesis characterized by leaky, tortuous, and chaotic vasculature is one of the hallmarks of cancers and is significantly correlated to poor prognosis. Disorganized angiogenesis leads to poor perfusion of anti-cancer drugs and limits access to immune cells. Hence, impeding angiogenesis is one of the attractive therapeutic targets to inhibit progression and metastasis in...

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PMID: 34755911
DOI: 10.1111/boc.202100015

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