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Article

Specific blood metabolite associations with Gout: a Mendelian randomization study.

European journal of clinical nutrition - 1 Jan 2025

Zeng Huiqiong, Lai Junda, Liu Zhihang, Liu Wei, Zhang Ye

Abstract excerpt

OBJECTIVE: Gout, common metabolic disorders, have poorly understood links with blood metabolites. Exploring these relationships could enhance clinical prevention and treatment strategies. METHODS: We applied bidirectional two-sample Mendelian randomization (MR) analysis, using data from a genome-wide association (GWAS) study of 486 blood metabolites. Gout data was obtained from FinnGen R8 (7461 gout and 221,323...

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PMID: 39215202
DOI: 10.1038/s41430-024-01497-7
PMCID: PMC11717691

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