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Causal Relationship Between Blood Metabolites and Prostate Cancer Risk: A Two-Sample Mendelian Randomization Study.

Molecular carcinogenesis - 1 Aug 2025

Liu Shuai, Zhu Jingjing, Zhang Huizhen, Zhong Hua, Wong Hoi Tung Hilton, Wang Liang, Wu Lang

Abstract excerpt

Recent research has increasingly suggested an association between changes in specific blood metabolites and prostate cancer (PCa) development. However, it remains unclear whether these observed associations represent a causal relationship. To reveal the potential causal associations between blood metabolites and PCa risk, we conducted a comprehensive two-sample Mendelian randomization (MR) analysis. We used...

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PMID: 40387704
DOI: 10.1002/mc.23929
PMCID: PMC12974314

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