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Article

Influence of IL17A polymorphisms (rs2275913 and rs3748067) on the susceptibility to ulcerative colitis.

Clinical and experimental medicine - 1 Nov 2013

Hayashi Ranji, Tahara Tomomitsu, Shiroeda Hisakazu, Saito Takashi, Nakamura Masakatsu, Tsutsumi Mikihiro, Shibata Tomoyuki, Arisawa Tomiyasu

Abstract excerpt

Interleukin-17A plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines. We investigated the association between ulcerative colitis (UC) and polymorphisms of IL17A, rs2275913 (-197 G > A), and rs3748067 (*1249 C > T). The study was performed in 475 healthy subjects (controls) and 202 with UC (UC cases), including 113 controls and 64 UC cases from previous...

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PMID: 22955700
DOI: 10.1007/s10238-012-0206-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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