Article
Susceptibility to ulcerative colitis in Hungarian patients determined by gene-gene interactions.
World journal of gastroenterology - 7 Jan 2014
Sarlos Patricia, Varszegi Dalma, Csongei Veronika, Magyari Lili, Jaromi Luca, Nagy Lajos, Melegh Bela
Abstract excerpt
AIM: To study the inflammatory bowel disease-5 locus (IBD5) and interleukin-23 receptor (IL23R) gene variants in UC patients and test for gene-gene interaction. METHODS: The study population (n = 625) was comprised of 320 unrelated ulcerative colitis (UC) patients with Caucasian origin and 316 age- and gender-matched, healthy controls. Five variants in the IBD5 locus (IGR2198a_1 rs11739135, IGR2096a_1 rs12521868,...
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