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Article

Nucleotide polymorphism-based study utilizes human plasma liposomes to discover potential therapeutic targets for intervertebral disc disease.

Frontiers in endocrinology - 1 Jan 2024

Chen Ding-Qiang, Que Zhi-Qiang, Xu Wen-Bin, Xiao Ke-Yi, Sun Nai-Kun, Song Hong-Yu, Feng Jin-Yi, Lin Guang-Xun, Rui Gang

Abstract excerpt

Background: While intervertebral disc degeneration (IVDD) is crucial in numerous spinally related illnesses and is common among the elderly, the complete understanding of its pathogenic mechanisms is still an area of ongoing study. In recent years, it has revealed that liposomes are crucial in the initiation and progression of IVDD. However, their intrinsic mediators and related mechanisms remain unclear. With...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39211445
DOI: 10.3389/fendo.2024.1403523
PMCID: PMC11357925

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