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Article

Potentially causal association between immunoglobulin G N-glycans and cardiometabolic diseases: Bidirectional two-sample Mendelian randomization study.

International journal of biological macromolecules - 1 Nov 2024

Meng Xiaoni, Liu Di, Cao Meiling, Wang Wei, Wang Youxin

Abstract excerpt

BACKGROUND: Observational studies support that altered immunoglobulin G (IgG) N-glycosylation and inflammatory factors are associated with cardiometabolic diseases (CMDs); nevertheless, the causality between them remains unclear. METHODS: Two-sample Mendelian randomization (MR) analyses were conducted to systematically investigate the bidirectional causality between IgG N-glycans and nine CMDs in both East Asians...

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Identifiers

PMID: 39208880
DOI: 10.1016/j.ijbiomac.2024.135125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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