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Article

Causal relationships between circulating inflammatory factors and IgA vasculitis: a bidirectional Mendelian randomization study

11 Sept 2023

Abstract excerpt

Background IgA vasculitis (IgAV) is an immune-associated vasculitis, yet its exact etiology remains unclear. Here, we explore the interaction between IgAV and inflammatory factors using bidirectional Mendelian randomization (MR). Methods We conducted a bidirectional summary-level MR analysis to delineate the causality of C-reactive protein (CRP), procalcitonin (PCT), and 41 circulating inflammatory regulators...

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PMID: 37753071
DOI: 10.3389/fimmu.2023.1248325

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