Article
Proteomics Identify Clinical Phenotypes and Predict Functional Outcomes in Heart Failure With Preserved Ejection Fraction: Insights From VITALITY-HFpEF.
Circulation. Heart failure - 1 Sept 2024
deFilippi Christopher R, Shah Palak, Shah Sanjiv J, Alemayehu Wendimagegn, Lam Carolyn S P, Butler Javed, Roessig Lothar, O'Connor Christopher M, Westerhout Cynthia M, Armstrong Paul W
Abstract excerpt
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome that may emerge from overlapping systemic processes associated with comorbidities. We assessed whether unique clusters of circulating proteins are associated with specific clinical characteristics and functional status at baseline and follow-up in a well-phenotyped cohort of patients with HFpEF. METHODS: We evaluated...
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