Article
Identification of novel pheno-groups in heart failure with preserved ejection fraction using machine learning.
Heart (British Cardiac Society) - 1 Mar 2020
Hedman Åsa K, Hage Camilla, Sharma Anil, Brosnan Mary Julia, Buckbinder Leonard, Gan Li-Ming, Shah Sanjiv J, Linde Cecilia M, Donal Erwan, Daubert Jean-Claude, Mälarstig Anders, Ziemek Daniel, Lund Lars
Abstract excerpt
OBJECTIVE: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome. We aimed to derive HFpEF phenotype-based groups ('phenogroups') based on clinical and echocardiogram data using machine learning, and to compare clinical characteristics, proteomics and outcomes across the phenogroups. METHODS: We applied model-based clustering to 32 echocardiogram and 11 clinical and laboratory...
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