Article
Transcriptome analysis of papillary thyroid cancer harboring telomerase reverse transcriptase promoter mutation.
Head & neck - 1 Nov 2018
Chien Ming-Nan, Yang Po-Sheng, Hsu Yi-Chiung, Liu Tsang-Pai, Lee Jie-Jen, Cheng Shih-Ping
Abstract excerpt
BACKGROUND: Telomerase reverse transcriptase (TERT) promoter mutations have recently been identified as an important prognostic factor in thyroid cancer. Studies suggest that TERT may have noncanonical functions beyond telomere maintenance. METHODS: Clinicopathological information and transcriptome data for papillary thyroid carcinoma (PTC) samples were obtained from The Cancer Genome Atlas (TCGA). Propensity...
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