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Article

High-proportion spliced-in titin truncating variants in African and European ancestry in the All of Us Research Program.

Nature cardiovascular research - 1 Feb 2024

Shetty Naman S, Pampana Akhil, Patel Nirav, Li Peng, Arora Garima, Arora Pankaj

Abstract excerpt

High-proportion spliced-in titin truncating variants (hiPSI TTNtvs) have been associated with an increased risk of atrial fibrillation, dilated cardiomyopathy (DCM) and heart failure in individuals of European ancestry1. However, similar data in individuals of African ancestry are lacking. Here we examined the association of hiPSI TTNtvs with atrial fibrillation, DCM and heart failure in individuals of African...

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Identifiers

PMID: 39196186
DOI: 10.1038/s44161-023-00417-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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