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Article

BRCA1/2 mutations and outcomes among Middle Eastern patients with early-onset breast cancer in Oman.

The oncologist - 6 Dec 2024

Al Amri Waleed S, Al Amri Ahmed H, Al Abri Aisha, Hughes Thomas A, Al Lawati Fatma

Abstract excerpt

BACKGROUND: High prevalence of early-onset breast cancer (EOBC) has been reported in Middle Eastern populations. For example, in Oman more than 50% of patients with breast cancer (BC) are under age 45 at diagnosis. Causes for this high incidence are unknown. Germline BRCA gene mutations have been associated with EOBC, however, prevalence of these mutations and how they relate to EOBC in Oman has not been...

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Source

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Identifiers

PMID: 39187384
DOI: 10.1093/oncolo/oyae214
PMCID: PMC11630774

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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