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The spectrum of BRCA1 and BRCA2 mutations and clinicopathological characteristics in Chinese women with early-onset breast cancer.

Breast cancer research and treatment - 1 Apr 2020

Chen Lili, Fu Fangmeng, Huang Meng, Lv Jinxing, Zhang Wenzhe, Wang Chuan

Abstract excerpt

PURPOSE: BRCA1/2 mutations represent a high risk of breast cancer and are related to early-onset breast cancer. However, few studies have reported the relationship between BRCA1/2 mutations and their clinical characteristics in early-onset breast cancers. This study is the first article that characterizes the risk factor profiles in Chinese patients selected by the age of onset (≤ 40 years old). We found some...

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PMID: 32072338
DOI: 10.1007/s10549-020-05573-x

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