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Article

Exome sequencing reveals new insights into the germline landscape of inflammatory breast cancer among Tunisian patients.

Journal of translational medicine - 14 Oct 2025

Boujemaa Maroua, Hamdi Yosr, Guidara Souhir, Souissi Amal, Bouaziz Hanen, Mejri Nesrine, Aloulou Samir, Mahjoub Najet, Chaabane Kais, Hakim Hana, Boussen Hamouda, Dhiab Tarek Ben, Kamoun Salma, Ayadi Rahma, Driss Maha, Ayadi Aida, Radouani Fouzia, Fakhkhari Meryem, Khyatti Meriem, Abdelhak Sonia, Sadki Khalid, Boubaker Mohamed Samir, Rebai Ahmed, Cherif Boutheina

Abstract excerpt

BACKGROUND: Inflammatory breast cancer (IBC) is a rare and aggressive form of breast cancer, characterized by distinct clinicopathological features and a relatively high frequency in North African countries. While several studies have explored the genetic basis of breast cancer, limited research has looked into the specific genetic features of this aggressive form. This study aims to investigate the genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41088366
DOI: 10.1186/s12967-025-07027-8
PMCID: PMC12522356

Genes

RAD54L
ABRAXAS1
BRCA2
IFNAR2
MTHFR
XRCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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