Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of circulating cytokines on the risk of systemic lupus erythematosus: Mendelian randomization and observational study.

Immunogenetics - 1 Dec 2024

Xue Dan, Qian Yu, Tu Xiao, He Mu, Xing Fengling, Ren Yunqing, Yuan Chengda

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder, the etiology of which involves the alterations in circulating cytokine levels. However, the cause-and-effect relationships and in-depth clinical relevance of them remain to be systematically investigated. We conducted a two-sample Mendelian randomization (MR) study to assess the causality of circulating cytokine levels and SLE and found that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-18

Share to Lupus Erythematosus, Systemic

Share to Lupus Nephritis

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 39183206
DOI: 10.1007/s00251-024-01351-x
PMCID: PMC11496328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of circulating cytokines on the risk of systemic lupus erythematosus: Mendelian randomization and observational study.PMID 39183206Read ↗

Correlation between circulating levels of cytokines and the risk of systemic lupus erythematosus: results from a Mendelian randomization study and bioinformatics analysisSemantic proximity Read ↗

Exploring causal correlations between inflammatory cytokines and systemic lupus erythematosus: A Mendelian randomizationSemantic proximity Read ↗

The causal associations of inflammatory cytokines with obesity and systemic lupus erythematosus: A Mendelian randomization study.Semantic proximity Read ↗

Genetically predicted associations between circulating cytokines and autoimmune diseases: a bidirectional two-sample Mendelian randomization.Semantic proximity Read ↗

The Genomic Architecture of Circulating Cytokine Levels Points to Drug Targets for Immune-Related DiseasesSemantic proximity Read ↗

Genetically determined circulating levels ofcytokines and the risk of rheumatoid arthritisSemantic proximity Read ↗

The Genomic Architecture of Circulating Cytokine Levels Points to Drug Targets for Immune-Related DiseasesSemantic proximity Read ↗

The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseasesSemantic proximity Read ↗

Circulating Cytokines and Coronavirus Disease: A Bi-Directional Mendelian Randomization StudySemantic proximity Read ↗

Causal relationship between circulating cytokines and the risk of systemic sclerosis: A bidirectional Mendelian-randomization studySemantic proximity Read ↗

Mendelian randomization analysis links HLA-DR+ CD14- CD16+ monocytes to CCL19-driven ankylosing spondylitis risk.Semantic proximity Read ↗

Associations of the circulating levels of cytokines with the risk of myeloproliferative neoplasms: a bidirectional mendelian-randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.