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Article

Causal relationship between circulating cytokines and the risk of systemic sclerosis: A bidirectional Mendelian-randomization study

2023-12-20

Abstract excerpt

<h4>Objectives: </h4> Systemic sclerosis (SSc) is an autoimmune disease characterized by immune dysfunction, vasculopathy, and fibrosis. While cytokines likely contribute to SSc pathogenesis, it is unclear whether particular cytokines play a causal role. We aimed to investigate potential causal relationships between circulating cytokines and SSc using Mendelian randomization. Methods We conducted a bidirectional...

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Literature Corpus work
3fbfb902-e209-5727-8241-0243883c9455
DOI
10.21203/rs.3.rs-3754606/v1
Open publication

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Causal relationship between circulating cytokines and the risk of systemic sclerosis: A bidirectional Mendelian-randomization studyDOI 10.21203/rs.3.rs-3754606/v1
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