Article
MalariaFlow: A comprehensive deep learning platform for multistage phenotypic antimalarial drug discovery.
European journal of medicinal chemistry - 5 Nov 2024
Lin Mujie, Cai Junxi, Wei Yuancheng, Peng Xinru, Luo Qianhui, Li Biaoshun, Chen Yihao, Wang Ling
Abstract excerpt
Malaria remains a significant global health challenge due to the growing drug resistance of Plasmodium parasites and the failure to block transmission within human host. While machine learning (ML) and deep learning (DL) methods have shown promise in accelerating antimalarial drug discovery, the performance of deep learning models based on molecular graph and other co-representation approaches warrants further...
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