Article

Pre-trained molecular representations enable antimicrobial discovery

2024-03-11

Abstract excerpt

The rise in antimicrobial resistance poses a worldwide threat, reducing the efficacy of common antibiotics. Determining the antimicrobial activity of new chemical compounds through experimental methods is still a time-consuming and costly endeavor. Compound-centric deep learning models hold the promise to speed up this search and prioritization process. Here, we introduce a lightweight computational strategy for a...

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Literature Corpus work: e5bbaea4-6bb2-5879-8007-6971a60c3cf7
DOI: 10.1101/2024.03.11.584456

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