Article
Validation of GenProb-T1D and its clinical utility for differentiating types of diabetes in a biobank from a US healthcare system.
Journal of diabetes investigation - 1 Jan 2025
Billings Liana K, Shi Zhuqing, Mulford Ashley J, Wei Jun, Tran Huy, Ashworth Annabelle, Zheng S Lilly, Dunnenberger Henry M, Hulick Peter J, Sanders Alan R, Xu Jianfeng
Abstract excerpt
Atypical diabetes with overlapping clinical features of type 1 (T1D) and type 2 (T2D) is common and challenging diagnostically and for implementing effective treatment. Here, we validate a recently reported genetic probability of type 1 diabetes (GenProb-T1D) from the UK Biobank (UKB) for differentiating type 1 diabetes and type 2 diabetes in a diabetes patient cohort from a healthcare system-based biobank in the...
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