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Article

Comprehensive genomic and spatial immune infiltration analysis of survival outliers in extensive-stage small cell lung cancer receiving first-line chemoimmunotherapy.

International immunopharmacology - 15 Nov 2024

Jiang Yuxin, Xie Jingyuan, Cheng Qinpei, Cai Zijing, Xu Ke, Lu Wanjun, Wang Fufeng, Wu Xiaoying, Song Yong, Lv Tangfeng, Zhan Ping

Abstract excerpt

BACKGROUND: A minority of patients with extensive-stage small cell lung cancer (ES-SCLC) exhibit prolonged survival following first-line chemoimmunotherapy, which warrants the use of reliable biomarkers. Here, we investigated the disparities in genomics and immune cell spatial distribution between long- and short-term survival of patients with ES-SCLC. METHODS: We retrospectively recruited 11 long-term (>2 years)...

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Identifiers

PMID: 39151386
DOI: 10.1016/j.intimp.2024.112901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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