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Article

Altering traits and fates of wild populations with Mendelian DNA sequence modifying Allele Sails.

Nature communications - 13 Aug 2024

Johnson Michelle L, Hay Bruce A, Maselko Maciej

Abstract excerpt

Population-scale genome modification can alter the composition or fate of wild populations. Synthetic gene drives provide one set of tools, but their use is complicated by scientific, regulatory, and social issues associated with transgene persistence and flow. Here we propose an alternative approach. An Allele Sail consists of a genome editor (the Wind) that introduces DNA sequence edits, and is inherited in a...

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Share to Alleles
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39138152
DOI: 10.1038/s41467-024-50992-9
PMCID: PMC11322531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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