Article
CTSG polymorphisms in Chinese children with type 1 diabetes mellitus.
Journal of tropical pediatrics - 13 Jul 2024
Li Jiaci, Zhang Mingying, Zhang Shuyue, Wang Rui, Cai Yingzi, Chen Xiaofang, Dong Yan, Wang Ping, Shu Jianbo, Lv Ling, Cai Chunquan
Abstract excerpt
Cathepsin G (CTSG) plays an important role in the regulation of immune processes. Accumulated studies show that CTSG is involved in the onset and development of type 1 diabetes mellitus (T1DM). As the genetic background of T1DM varies widely among populations, we aimed to study the relationship between genetic polymorphisms in CTSG and T1DM susceptibility in Chinese populations. A total of 141 patients with T1DM...
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