Article
Association between SNPs in the promoter region in cathepsin S and risk of asthma in Chinese Han population.
European review for medical and pharmacological sciences - 1 May 2016
Zhou P-P, Zhang W-Y, Li Z-F, Chen Y-R, Kang X-C, Jiang Y-X
Abstract excerpt
OBJECTIVE: Cathepsin S (CTSS) is a lysosomal cysteine protease and is predominantly expressed in antigen-presenting cells, which plays an important role in the allergic response. In this study, we explored the association between single nucleotide polymorphisms (SNPs) in the promotor regions in CTSS and risk of asthma. PATIENTS AND METHODS: A total of 591 cases and 621 controls were recruited for this study. Five...
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