Identification of genetic subtypes in follicular lymphoma.

doi:10.1038/s41408-024-01111-w

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Article

Identification of genetic subtypes in follicular lymphoma.

Blood cancer journal - 7 Aug 2024

Shelton Victoria, Detroja Rajesh, Liu Ting, Isaev Keren, Silva Anjali, Passerini Verena, Bakhtiari Mehran, Calvente Lourdes, Hong Michael, He Michael Y, Modi Saloni, Hershenfeld Samantha A, Ludvigsen Maja, Madsen Charlotte, Hamilton-Dutoit Stephen, d'Amore Francesco Annibale, Brodtkorb Marianne, Johnson Nathalie A, Baetz Tara, LeBrun David, Tobin Josh W D, Gandhi Maher K, Mungall Andrew J, Xu Wei, Ben-Neriah Susana, Steidl Christian, Delabie Jan, Tremblay-LeMay Rosemarie, Jegede Opeyemi, Weigert Oliver, Kahl Brad, Evens Andrew M, Kridel Robert

Abstract excerpt

Follicular lymphoma (FL) exhibits considerable variability in biological features and clinical trajectories across patients. To dissect the diversity of FL, we utilized a Bernoulli mixture model to identify genetic subtypes in 713 pre-treatment tumor tissue samples. Our analysis revealed the existence of five subtypes with unique genetic profiles that correlated with clinicopathological characteristics. The...

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Identifiers

PMID: 39112453
DOI: 10.1038/s41408-024-01111-w
PMCID: PMC11306633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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