Article
Integrative genomic and transcriptomic analysis reveals genetic alterations associated with the early progression of follicular lymphoma.
British journal of haematology - 1 Sept 2023
Gao Fenghua, Liu Hengqi, Meng Xiangrui, Liu Jing, Wang Jiesong, Yu Jingwei, Liu Xia, Liu Xianming, Li Lanfang, Qiu Lihua, Qian Zhengzi, Zhou Shiyong, Gong Wenchen, Meng Bin, Ren Xiubao, Golchehre Zahra, Chavoshzadeh Zahra, He Jin, Zhang Huilai, Wang Xianhuo
Abstract excerpt
Follicular lymphoma (FL), the most common indolent lymphoma, is a clinically and genetically heterogeneous disease. However, the prognostic value of driver gene mutations and copy number alterations has not been systematically assessed. Here, we analysed the clinical-biological features of 415 FL patients to identify variables associated with disease progression within 24 months of first-line therapy (POD24)....
Topics
- Humans
- Lymphoma, Follicular
- Transcriptome
- Phosphatidylinositol 3-Kinases
- Prognosis
- Mutation
- Gene Expression Profiling
- Genomics